Carsil Forte 90 mg 30 capsules by Sopharma
Description
Carsil (Milk thistle) is well known herbal supplement for its hepatoprotectant and antioxidant activities. Liver is the key organ of metabolism and excretion is continuously and variedly exposed to xenobiotics because of its strategic placement in the body. Toxins absorb from the intestinal tract first enter the liver resulting in a variety of liver disorders. Thus, liver diseases remain one of the serious health problems. Liver damage ranges from acute hepatitis to hepatocellular carcinoma, being caused through apoptosis, necrosis, inflammation, immune response, fibrosis, ischemia, altered gene expression etc.
Silybum marianum L. (Milk thistle), a member of Carduus marianum family, is an ancient medicinal plant which has been used for centuries for treatment of different diseases such as liver and gallbladder disorders, protecting liver against snake bite and insect stings, mushroom poisoning and alcohol abuse. This plant grows in Kashmir, North America, Canada and Mexico with large leaves and a reddish-purple flower that are all thorny and the medicinal part of the plant is either the seeds or fruits.
Silymarin (Milk Thistle) is the active component of this herb, which is a complex of other components, mainly silybin A, silybin B, isosilybin A, isosilybin B and also other flavonolignants such as silychristin, neosilyhermin, silyhermin and silydianin.
Mechanism of Action
Silymarin has cytoprotection activities due to its antioxidant activity and radical scavenging. The possible known mechanisms of action of silymarin protection are blockade and adjustment of cell transporters, p-glycoprotein, estrogenic and nuclear receptors.
Silymarin anti-inflammatory effects through reduction of TNF-α, protective effects on erythrocyte lysis and cisplatin-induced acute nephrotoxicity have been indicated in some studies. Silymarin has also inhibited apoptosis and follicular development in patients undergoing IVF.
Moreover, people used this herb for centuries as a natural treatment for upper gastrointestinal tract and digestive problems, liver and biliary tract diseases, menstrual disorders and varicose veins.
What are the benefits of Carsil
Silymarin (Milk Thistle) has antioxidant, immunomodulatory, antifibrotic, antiproliferative, and antiviral properties. Silymarin has a short half-life and quick conjugation in the liver and principal excretion in bile. In means of controlling hepatic inflammation in vivo, patients should use high or repeated oral doses. Carsil Forte is a potent herbal supplement containing 90 mg of Silymarin which is a higher dose than the regular Carsil.
How To Use
Adults and children 12 years or older: take 1 capsule 3 times a day for severe liver damage.
Take 1 capsule once or twice a day for mild to moderate cases.
For the prevention of chemical intoxications: take 1-2 capsules a day.
Duration of treatment is at least 3 months.
Not for children younger than 12 years old.
Store at room temperature no more than 25C.
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